Professor Martin Feelisch

Martin Feelisch

Martin is Professor of Experimental Medicine and Integrative Biology within Medicine at the University of Southampton.

He has a long-standing interest in analytical chemistry, cardiovascular pharmacology, nutrition and metabolism, photobiology, disease mechanisms, and the chemical biology of nitric oxide (NO), nitroxyl (HNO), and sulfide in its various forms (H2S, HS-, R-SSxH). His more recent interests focus on the interconversion of nitrogen and sulfur species and related storage forms in the context of intermediary metabolism, the role of sunlight and the skin microbiome for cardiovascular health, mechanisms of adaptation to hypoxia and altitude as well as the significance of chemical interactions between reactive oxygen, nitrogen and sulfur species (ROS, RNS, RSS) for mitochondrial function and redox signalling in humans. Work in his laboratory is both hypothesis- and curiosity-driven and includes basic as well as translational research projects in all of the above areas. Current development efforts in his lab focus on targeted metabolomic approaches (‘redox metabolomics’) to disentangle the mechanisms of redox regulation in health and disease.